Reference Architecture

    Clinical Research AI Inside the Hospital Boundary

    A research hospital wanted AI-assisted clinical document analysis while keeping PHI inside its own boundary. Hosted AI services could not guarantee the required data residency or audit posture.

    At a glance
    Zero
    PHI Egress
    Role + study
    Access Model
    100%
    Audit Coverage
    Healthcare
    Sovereign AI
    Anonymized — research hospital
    HIPAA
    Clinical Research
    Document AI
    Sovereign AI

    The operational problem

    Research teams want retrieval over clinical text, but the governing constraint is that protected health information cannot leave the institution and every access must be attributable. That pushes the entire pipeline — embedding, retrieval, inference, and logging — inside the hospital boundary.

    What Enfuse built

    • On-prem inference and embedding services sized to the research workload
    • PHI detection and redaction at ingest, with reversible tokens for authorized roles
    • Study- and role-scoped retrieval with consent-status filtering
    • End-to-end audit logging of prompts, retrieved documents, and outputs
    • Evaluation harness for clinical extraction accuracy before each model change

    Architecture

    • Ingest — de-identification and indexing of clinical documents
    • Retrieve — access-scoped RAG over the research corpus
    • Reason — on-prem model inference with policy enforcement
    • Record — immutable audit trail for compliance review

    Hardware and software

    • On-prem GPU servers
    • Sovereign Runtime with DocuFlow retrieval service
    • Hospital identity provider, SIEM, and existing EHR interfaces

    Deployment environment

    On-premises hospital datacenter. No external model API calls.

    Results

    • Retrieval-assisted review of clinical documents without data egress
    • Attributable, auditable access for every request

    Reference architecture. Describes the deployment pattern rather than measured outcomes at a named institution.

    Next step

    Discuss this pattern against your environment

    Bring your constraints — sensors, security boundary, latency budget — and we will tell you what is realistic.